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Special warnings: As with all vaccines, VERORAB may not protect 100% of people vaccinated. Use with caution on subjects with a known allergy to neomycin polymyxin B, to streptomycin (present in trace form in the vaccine) or to any antibiotic of the same group.
Do not inject by the intravascular route: make sure that the needle does not enter a blood vessel. Immunoglobulins and rabies vaccine must not be associated in the same syringe or injected at the same site.
A serological test (neutralizing antibody assay using the RFFIT (Rapid Fluorescent Focus Inhibition Test) test) must be conducted on persons subject to continuous exposure (every 6 months) and maybe conducted every 2 to 3 years after the booster dose after 1 and 5 years in person subject to discontinuous exposure according to the assessed exposure risk.
For immunodeficient subjects, this test may be conducted 2 to 4 weeks following the vaccination. If the result of the test demonstrates an antibody titre < 0.5 IU/mL, a booster injection or an additional injection, for immunodeficient subjects, is justified.
This vaccine must never be administered by the intravascular route.
As with all vaccines, VERORAB may not protect 100% of people vaccinated.
Precautions for use: Inform the doctor in the event of known allergy to neomycin, polymyxin B, streptomycin, or to any antibiotic of the same group due to the use of these substances during production.
Injection schedule recommendations should be followed scrupulously.
As with all injectable vaccines, VERORAB should be administered with caution in subjects with thrombocytopenia or coagulation disorders as intramuscular injection may induce bleeding in these subjects.
The potential risk of apnoea and the need for respiratory monitoring for 48-72 h should be considered when administering the primary immunization series to very premature infants (born ≤ 28 weeks of gestation) and particularly for those with a previous history of respiratory immaturity. As the benefit of vaccination is high in this group of infants, vaccination should not be withheld or delayed.
Anxiety-related reactions, including vasovagal reactions (syncope), hyperventilation or stress related reactions can occur following, or even before, any vaccination as a psychogenic response to the needle injection. This can be accompanied by several neurological signs such as transient visual disturbance and paraesthesia. It is important that procedures are in place to avoid injury from faints.
If there is any doubt, do not hesitate to consult the doctor or the pharmacist.
Effect on ability to drive and use machines: Post-vaccination dizziness was frequently reported. It can temporarily affect the ability to drive or use machines.
